2-(1-piperidinyl)acetic acid - Names and Identifiers
2-(1-piperidinyl)acetic acid - Physico-chemical Properties
Molecular Formula | C7H13NO2
|
Molar Mass | 143.18 |
Density | 1.103±0.06 g/cm3(Predicted) |
Melting Point | 214-216 °C(Solv: chloroform (67-66-3)) |
Boling Point | 252.2±23.0 °C(Predicted) |
Flash Point | 106.3 °C |
pKa | 2.47±0.10(Predicted) |
Storage Condition | 2-8℃ |
2-(1-piperidinyl)acetic acid - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Risk Codes | 41 - Risk of serious damage to eyes
|
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S39 - Wear eye / face protection.
|
Hazard Class | IRRITANT |
2-(1-piperidinyl)acetic acid - Introduction
1-Piperidineacetic acid(1-Piperidineacetic acid) is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
1-Piperidineacetic acid is a white to light yellow solid. It is stable at room temperature, soluble in organic solvents such as ethers and alcohols, and insoluble in water.
Use:
1-Piperidineacetic acid is a commonly used organic synthesis intermediate. It is commonly used in the preparation of biologically active compounds, such as pharmaceuticals and pesticides. It can also be used for base catalysts and protecting groups in organic synthesis reactions.
Method:
The preparation method of 1-Piperidineacetic acid is generally obtained by reacting diethylene carbonate with 3-benzyl -3-piperidinecarboxaldehyde. The specific steps are as follows: the reaction of diethylene carbonate with 3-benzyl-3-piperidine formaldehyde under neutral conditions, after dehydration and acidification treatment, to obtain 1-Piperidineacetic acid.
Safety Information:
1-Piperidineacetic acid is relatively safe under regular operations. However, it can be irritating to the skin, eyes and respiratory system. Appropriate personal protective equipment (such as lab gloves and goggles) is recommended for use or handling. In addition, compound waste needs to be stored and disposed of properly and safely in accordance with local regulations.
Last Update:2024-04-09 20:52:54